Unless they are documented and signed off, the project itself might have quite a few unknowns at the very onset.

除非将其形成文档，并最终签署确定，否则刚一开始项目本身就可能有很多未知的地方。

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At the very onset, a proposal manager needs to identify the exact IT skill sets required to develop the proposal.

在开始时，提案经理需要准确地确定开发提案所需的各种IT技能。

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The median age at onset for generalized anxiety disorder is 30 years; however, age at onset is spread over a very broad range.

广泛性焦虑障碍起病的中位年龄为30岁，而起病年龄的跨度很大。

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Magazines were one of the earliest mechanisms for social grouping, and before the onset of the digital age, publishers were very good at building and monetizing highly valuable networks of similar people built around different content verticals.

FORBES: For Magazines, The Digital Future Lies Beyond The iPad